Status:
ENROLLING_BY_INVITATION
Midazolam or Fentanyl as Adjuvants to Epidural Bupivacaine Plus Dexamethasone for Analgesia
Lead Sponsor:
Zagazig University
Conditions:
Lumbar Spine Fixation
Eligibility:
All Genders
21-64 years
Phase:
NA
Brief Summary
The purpose of this study is to compare better postoperative analgesia after lumbar spine Fixation using either epidural bupivacaine with midazolam or fentanyl with the combination of dexamethasone.
Detailed Description
After being informed about the study and potential risks. A computer-generated randomization table will randomize all patients giving written consent into 2 groups, each containing 51 patients. In the...
Eligibility Criteria
Inclusion
- Written informed consent from the patient.
- Physical status: ASA 1\& II.
- BMI = (25-30 kg/m2).
- Type of operation: elective lumbar spine Fixation.
Exclusion
- Altered mental state.
- Patients with known history of allergy to study drugs.
- Advanced hepatic, renal, cardiovascular, and respiratory diseases.
- Patients with chronic pain.
- Contraindications of regional anesthesia, e.g., allergy to local anesthetics, coagulopathy, or septic focus at site of injection.
Key Trial Info
Start Date :
April 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT06898697
Start Date
April 1 2025
End Date
December 1 2025
Last Update
March 27 2025
Active Locations (1)
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1
Faculty of Medicine,Zagazig University
Zagazig, Egypt, 44519