Status:
RECRUITING
The Effects of Intravenous Iron on Mobility in Elderly Patients Following Hip Fracture Surgery
Lead Sponsor:
Soren Overgaard
Collaborating Sponsors:
University Hospital Bispebjerg and Frederiksberg
Copenhagen University Hospital at Herlev
Conditions:
Hip Fracture
Anemia
Eligibility:
All Genders
65+ years
Phase:
PHASE4
Brief Summary
The primary aim of this clinical trial is to investigate the effects of intravenous iron on recovery in mobility compared to the pre-fracture level in patients with a hip fracture The main questions ...
Eligibility Criteria
Inclusion
- 65 years of age or older
- Acute proximal femur fracture surgery
- A hemoglobin measurement ≤6.5 mmol/L (10.5 g/dL) on day 1 to 5 postoperatively
- Independent prefracture indoor walking ability, indoor NMS ≥ 2
- Ability to speak and understand Danish
- Able to provide informed consent on the participants own behalf
Exclusion
- Known allergy to intravenous iron
- Residing permanently at a nursing home
- Hematological conditions with a risk of iron overload e.g. haemochromatosis, hemosiderosis, or where alternative treatments are necessary e.g. haematological malignancies
- Other contraindication to iron treatment, e.g. severe liver cirrhosis and hepatitis
- Severe uncontrolled infection as assessed by the responsible clinician (e.g. bacteraemia or sepsis)
- Plasma sodium levels below 125 or above 150 mmol/L on the day of inclusion
- Renal replacement therapy
- Severe dementia assessed by physician
- Recent intravenous iron injection, 4 weeks prior to surgery
- Patient declared terminally ill
- Pathologic Fracture
Key Trial Info
Start Date :
June 9 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 14 2027
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT06898814
Start Date
June 9 2025
End Date
September 14 2027
Last Update
December 10 2025
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Orthopedic Surgery and Traumatology, Bispebjerg, Copenhagen University Hospital
Copenhagen NV, Denmark, 2400
2
Department of Orthopedic Surgery and Traumatology, Herlev, Copenhagen University Hospital
Herlev, Denmark, 2730
3
Department of Orthopaedic Surgery, Odense and Svendborg University Hospital
Odense C, Denmark, 5000