Status:
ACTIVE_NOT_RECRUITING
Ventilator Settings and Outcomes in Pediatric Patients on ECMO for Severe Respiratory Failure
Lead Sponsor:
University Medical Center Groningen
Collaborating Sponsors:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions:
Critical Illness
Respiratory Failure (Pediatric Patients)
Eligibility:
All Genders
29-18 years
Brief Summary
This study aims to describe the effects of ECMO initiation on the intensity of ventilation in the first 24 hours after ECMO initiation and to explore associations between changes in ventilation intens...
Detailed Description
Rationale: Despite the growing use of ECMO in critically ill pediatric patients, uncertainties remain to what extent adjustments of ventilator settings after ECMO initiation are associated with morta...
Eligibility Criteria
Inclusion
- Patients (aged ≥29 days to ≤18 years) receiving ECMO between January 1, 2012, and December 31, 2022, in an ELSO affiliated center; and
- Requiring ECMO for a pulmonary indication.
Exclusion
- Patients with missing ventilatory variables required to assess ventilation intensity;
- patients who were lost to follow up with respect to hospital mortality.
Key Trial Info
Start Date :
September 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2025
Estimated Enrollment :
750 Patients enrolled
Trial Details
Trial ID
NCT06899009
Start Date
September 1 2024
End Date
December 31 2025
Last Update
March 27 2025
Active Locations (1)
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1
University Medical Center Groningen
Groningen, Netherlands