Status:

RECRUITING

Gut Health in Children With Cancer

Lead Sponsor:

Great Ormond Street Hospital for Children NHS Foundation Trust

Conditions:

AML (Acute Myelogenous Leukemia

HLH

Eligibility:

All Genders

1-16 years

Brief Summary

The purpose of this study is to observe the impact leukaemia treatment has on gut health (microbiomes) and how quickly the gut health recovers after leukamia treatment. The gut microbiome has a number...

Detailed Description

Acute myeloid leukaemia (AML) is an aggressive cancer that occurs due to the clonal expansion of immature white blood cells, known as blasts (Chaudhury et al., 2018) with generally poor outcomes compa...

Eligibility Criteria

Inclusion

  • \- Consented to partake in the study
  • Aged 0-16 years old
  • Diagnosed with AML/HLH/ Burkits

Exclusion

  • 17 years old + (treated at UCL adolescent unit)
  • Inflammatory bowel disease: ulcerative colitis or Crohn's disease
  • Children who had previously been treated with chemotherapy in another institution age

Key Trial Info

Start Date :

January 30 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 30 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06899581

Start Date

January 30 2025

End Date

October 30 2026

Last Update

March 28 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Great Ormond Street Hospital

London, United Kingdom, WC1N 3JH