Status:
RECRUITING
Collection of Blood and Tissue Samples From Patients With Primary Liver Cancer.
Lead Sponsor:
Fondazione IRCCS Policlinico San Matteo di Pavia
Conditions:
Hepatocellular Carcinoma (HCC)
Cholangiocarcinoma
Eligibility:
All Genders
18-90 years
Brief Summary
The project aims to collect blood, tissue samples, and clinical data from patients with primary liver cancer (mainly hepatocellular carcinoma and intrahepatic cholangiocarcinoma) undergoing systemic t...
Detailed Description
The project aims to collect blood and tissue samples, as well as clinical data, from patients with primary liver cancer undergoing systemic therapy, surgical resection, or liver biopsy. Primary liver...
Eligibility Criteria
Inclusion
- Primary liver cancer (hepatocellular carcinoma or intrahepatic cholangiocarcinoma)
- Signed informed consent
- Patient eligible to start first-line systemic therapy
- Patient eligible for surgical resection
Exclusion
- Concurrent conditions with a life expectancy of less than 12 months
- Autoimmune or chronic inflammatory diseases
- Substance abuse dependency
- Other active extrahepatic malignancies or those treated within the last 3 years, except for the following exceptions:
- Tumors resected with curative intent and with no evidence of disease recurrence for \>3 years prior to signing the informed consent, considered at low risk of recurrence
- Adequately resected non-melanoma skin cancers or lentigo maligna with no evidence of metastasis
- Adequately treated carcinoma in situ of the cervix with no evidence of recurrence
- Prostatic intraepithelial neoplasia with no evidence of infiltrative disease
- Adequately treated non-invasive papillary urothelial tumors or urothelial carcinoma in situ
- HIV infection
- Lack of patient cooperation or failure to sign the informed consent
Key Trial Info
Start Date :
June 19 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
53 Patients enrolled
Trial Details
Trial ID
NCT06899854
Start Date
June 19 2023
End Date
March 1 2026
Last Update
April 3 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Pavia, Italy, 27100