Status:
COMPLETED
Radiographic Evaluation in Alveolar Preservation Using Platelet-rich Fibrin. Randomized Controlled Trial
Lead Sponsor:
Universidad Católica de Cuenca
Conditions:
Alveolar Bone Resorption
Preserving the Alveolar Ridge
Eligibility:
All Genders
17+ years
Phase:
NA
Brief Summary
This randomized controlled trial is designed to assess the use of platelet-rich fibrin (PRF), a biomaterial derived from a participant's own blood, in alveolar ridge preservation following premolar ex...
Detailed Description
This study is a randomized controlled clinical trial designed to investigate the application of platelet-rich fibrin (PRF) in post-extraction sites following orthodontically indicated premolar removal...
Eligibility Criteria
Inclusion
- Healthy individuals with no systemic diseases.
- Age range: 17 to 38 years old.
- Orthodontic indication for premolar extraction (two maxillary or two mandibular premolars).
- Candidates for orthognathic surgery or extraction of impacted/retained teeth (e.g., third molars with a relationship to critical anatomical structures).
- Clinical justification for CBCT imaging instead of standard radiographic -techniques.
Exclusion
- Patients with systemic diseases that may alter periodontal therapy outcomes.
- Platelet count below 200,000 mm³.
- Immunosuppressed patients.
- Pregnant or lactating women.
- Smokers.
- Patients taking medications that interfere with healing (e.g., bisphosphonates, corticosteroids, anticoagulants).
Key Trial Info
Start Date :
March 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 20 2024
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT06900036
Start Date
March 1 2023
End Date
November 20 2024
Last Update
March 28 2025
Active Locations (1)
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1
Universidad Catolica de Cuenca
Cuenca, Azuay, Ecuador