Status:

RECRUITING

The C-BRIDGE Study: China Bronchiectasis Research Involving Databases, Genomics, and Endotyping

Lead Sponsor:

Shanghai Pulmonary Hospital, Shanghai, China

Conditions:

Bronchiectasis Adult

Eligibility:

All Genders

18-85 years

Brief Summary

Bronchiectasis is a heterogeneous airway disease with diverse causes, making precise diagnosis, prognosis, and treatment response prediction challenging. Identifying patient subgroups (phenotypes) and...

Detailed Description

Bronchiectasis is a common, heterogeneous chronic airway disease that remains understudied in clinical and translational research. Although several phenotypes and endotypes have been identified-primar...

Eligibility Criteria

Inclusion

  • A prior CT scan confirming bronchiectasis, accompanied by a compatible clinical syndrome including cough, sputum production, and/or recurrent respiratory tract infections.
  • At the screening visit, participants must have been clinically stable for 4 weeks, defined as no antibiotic or corticosteroid treatment for a pulmonary exacerbation in the preceding 4 weeks.

Exclusion

  • Inability to provide informed consent
  • Age under 18 years
  • Patients with active tuberculosis
  • Use of antibiotics or corticosteroids for a pulmonary exacerbation within the past 4 weeks

Key Trial Info

Start Date :

April 6 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 31 2029

Estimated Enrollment :

1500 Patients enrolled

Trial Details

Trial ID

NCT06900062

Start Date

April 6 2025

End Date

January 31 2029

Last Update

November 25 2025

Active Locations (9)

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Page 1 of 3 (9 locations)

1

Lin Liu

Guiyang, Guizhou, China

2

Lei Song

Changchun, Jilin, China

3

Qian Qi

Jinan, Shangdong, China

4

He-feng Chen

Shanghai, Shanghai Municipality, China, 200433

The C-BRIDGE Study: China Bronchiectasis Research Involving Databases, Genomics, and Endotyping | DecenTrialz