Status:

NOT_YET_RECRUITING

#AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial.

Lead Sponsor:

Casper Rokx

Collaborating Sponsors:

ViiV Healthcare

Gilead Sciences

Conditions:

HIV Infection

HIV

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The #aware.hiv Europe study is a real-world, multicenter, stepped-wedge cluster randomized, effectiveness-implementation trial designed to evaluate whether the introduction of dedicated HIV teams in h...

Eligibility Criteria

Inclusion

  • Since this study involves screening individuals presenting to a specific hospital through a hospital-wide intervention, the inclusion and exclusion criteria are established at the hospital level.
  • Standard of care: HIV testing for HIV indicator conditions should be part of routine care in the country, and any prevailing guidelines on HIV testing and prevention policies can be integrated.
  • Management approval: Hospital management must be willing to allocate resources and provide authorization for the proposed activities, including Surveillance, Audit \& Feedback, Education \& Training, Linkage to Prevention, and fostering an Enabling Environment, including stigma reduction.
  • Resources: Assembling an HIV team led by a local HIV expert should be viable considering the available human resources.
  • Data collection: There should be an IT specialist and IT infrastructure capable of flagging a pre-defined set of HIV indicator conditions and monitoring the project's implementation effects with feedback loops to healthcare professionals.
  • Quality assurance: Continuous linkage for care and access to antiretroviral therapy must be assured.
  • Ethics and Regulatory Compliance: Provision for ethical and regulatory compliance is necessary.

Exclusion

  • Any hospital that does not meet the inclusion criteria will be excluded from participation. We will not use data of patients who have objected against the use of their data for research.

Key Trial Info

Start Date :

July 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2030

Estimated Enrollment :

5200 Patients enrolled

Trial Details

Trial ID

NCT06900829

Start Date

July 1 2025

End Date

February 1 2030

Last Update

March 28 2025

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#AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial. | DecenTrialz