Status:
NOT_YET_RECRUITING
Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines
Lead Sponsor:
Wake Forest University Health Sciences
Conditions:
Migraine
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.
Detailed Description
The purpose of this prospective, randomized, double-blinded study is to compare the relative efficacy and safety of intravenous magnesium in conjunction with intravenous prochlorperazine in the treatm...
Eligibility Criteria
Inclusion
- Age ≥ 18 years or older
- Able to provide informed consent
- English speaking
- Primary diagnosis of migraine. Patient with a previous diagnosis of migraine, who experience headaches with typical migraine features (e.g at least 2-3 of the following: recurrent, unilateral, pounding or throbbing in nature, associated with nausea), AND with a clinical exclusion of migraine mimics
Exclusion
- Pregnancy defined as a positive urine HCG
- Allergy or sensitivity to study drug
- Stated history of renal insufficiency
- Documented history of myasthenia gravis
- Consumption of study drug within 48 hours prior to enrollment
- Previously enrolled in this trial during a different patient encounter
Key Trial Info
Start Date :
December 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06904287
Start Date
December 1 2025
End Date
June 1 2027
Last Update
November 26 2025
Active Locations (1)
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1
Advocate Christ Medical Center Emergency Department
Oak Lawn, Illinois, United States, 60453