Status:
NOT_YET_RECRUITING
Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up: a Randomized Controlled Clinical Trial
Lead Sponsor:
Cairo University
Conditions:
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Moringa Oleifera
Eligibility:
All Genders
25-35 years
Phase:
NA
Brief Summary
This randomized clinical trial aimed to test the remineralization effect of laboratory prepared Moringa Oleifera based varnish compared to MI varnish (CPP-ACP) on incipient carious lesions. The study ...
Detailed Description
The aim of this randomized clinical trial is to evaluate the remineralization efficacy of Moringa Oleifera varnish in comparison to CPP-ACP Varnish on initial carious lesions over 6 months follow up p...
Eligibility Criteria
Inclusion
- Inclusion Criteria of participants:
- Presentation with at least one active WSLs on the study teeth at the start of the study.
- Good oral hygiene.
- Co-operative patients approving to participate in the trial.
- Have sufficient cognitive ability to understand consent procedures Inclusion criteria of teeth.
- Active non-cavitated initial carious lesions (ICDAS 1\&2)
- DIAGNOdent score between (8-15)
- Vital teeth with no signs or symptoms of irreversible pulpitis.
- No signs of clinical mobility.
- Teeth with healthy periodontium.
- Exclusion Criteria of participants:
- Participants with parafunctional habits or bruxism.
- Participants with dry mouth.
- Participants with systemic diseases or disabilities that may affect participation.
- Heavy smoking.
- Pregnancy.
- Lack of compliance.
- Severe or active periodontal disease.
- Cognitive impairment
- Exclusion criteria of teeth:
- DIAGNOdent score less than 8 and more than 15
- Untreated cavitated lesions or extensive restorations on the facial surfaces of the study teeth
- Intrinsic or extremely heavy extrinsic staining
- Periapical pathosis or signs of pulpal pathology.
- Non-vital tooth.
- Signs of pathological wear.
- Endodontically treated tooth.
- Severe periodontal affection or tooth indicated for extraction.
Exclusion
Key Trial Info
Start Date :
May 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06905379
Start Date
May 1 2025
End Date
January 1 2026
Last Update
April 1 2025
Active Locations (1)
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1
Hend Taha Hanafi Mahmoud
Cairo, Cairo Governorate, Egypt, 02022