Status:

RECRUITING

Bilateral Robot-assisted Upper Extremity Rehabilitation on Motor Recovery in People With Subacute Stroke

Lead Sponsor:

IRCCS San Raffaele Roma

Collaborating Sponsors:

Ministry of Health, Italy

Conditions:

Stroke

Sabacute Stroke

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to study the clinical effects of a robotic rehabilitation treatment through a bilateral exoskeleton (Bilateral Robot-Assisted Therapy-BRAT) during standard rehabilit...

Detailed Description

Cerebral stroke is one of the major causes of mortality and disability in the world. Upper limb disorders are evident up to 85% of stroke survivors and persist, even 6 months after the acute event, in...

Eligibility Criteria

Inclusion

  • Both sexes;
  • Age \>18 years;
  • Unilateral hemipyramidal syndrome as demonstrated by a brain CT or MRI;
  • Distance from acute event \< 6 months;
  • Modified Ashworth Scale (MAS) of shoulder, elbow, and wrist \<3;
  • Ability to understand and sign the informed consent for the study;
  • Ability to perform the study procedures.

Exclusion

  • Unstable general clinical conditions;
  • Bilateral pyramidal hemisyndrome severe visual impairment;
  • Recent injection of Botulinum Toxin to the affected upper limb or planned for the duration of the study;
  • Interruption of treatment for 1 week or 5 consecutive sessions;
  • Inability to adhere to the exercise program due to poor compliance;
  • Presence of neurological pathologies superimposed on the stroke event, psychiatric complications or personality disorders;
  • Presence of osteoarticular and neuromuscular pathologies that may compromise the motor skills of the upper limb;
  • Participants who have not signed the informed consent to the study.

Key Trial Info

Start Date :

May 19 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT06906588

Start Date

May 19 2024

End Date

December 31 2026

Last Update

April 4 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

San Raffaele Cassino

Cassino, Italy, Italy, 03043

2

IRCCS San Raffaele Roma

Rome, Italy, Italy, 00166

3

San Raffaele Sulmona

Sulmona, Italy, Italy, 67039