Status:

RECRUITING

Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D)

Lead Sponsor:

AdventHealth Translational Research Institute

Conditions:

Type 1 Diabetes

Celiac Disease

Eligibility:

All Genders

2+ years

Brief Summary

The purpose of this study is to identify people with T1D or celiac disease (CD) early in the course of their disease and to improve the methods of screening for these diseases.

Detailed Description

The study will screen people who may be at risk for T1D because they have at least one person in the family with probable T1D. It can be a parent or a sibling. It can also be a second-degree relative,...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Able to provide informed consent (adults 18 and above) and assent if seven or above. Legally authorized representative (LAR) is able to provide consent in case of minors or in case of adults unable to consent.
  • Children \> 2 years and adults at elevated risk of developing (or having misdiagnosed) clinically evident Stage 3 T1D because they have at least one of the following:
  • i. have one or more first- or second-degree family members (siblings, parents, cousins, aunts/uncles, grandparents) diagnosed with type 1 diabetes or ii. have other autoimmune diseases such as but not limited to celiac disease, Multiple sclerosis, rheumatoid arthritis or, thyroid disease or iii. Those diagnosed with other forms of diabetes which are suspected of being T1D because of a BMI ≤28 or progression to insulin dependence within 3 years from diagnosis.
  • Resides in the following Counties: Orange, Seminole, Osceola, Lake, Volusia, Brevard, Polk, Hillsborough.
  • Exclusion Criteria
  • People with a diagnosis of type stage 3T1D or T1D clinical definition per ADA Standards of Care
  • History of organ transplant
  • Be deemed unable or unlikely to comply with the protocol.
  • Presence of any condition that, in the opinion of the Investigator, compromises participant safety or data integrity or the participant's ability to complete study visit/s.

Exclusion

    Key Trial Info

    Start Date :

    March 11 2024

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    June 1 2026

    Estimated Enrollment :

    200 Patients enrolled

    Trial Details

    Trial ID

    NCT06908057

    Start Date

    March 11 2024

    End Date

    June 1 2026

    Last Update

    April 3 2025

    Active Locations (1)

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    AdventHealth Translational Research Institute

    Orlando, Florida, United States, 32804

    Accessing Care, Clinical Trials and Screening for Underserved Children and Adults With Type 1 Diabetes (ACCESS-T1D) | DecenTrialz