Status:
RECRUITING
Differences in Prosocial Behaviors and Related Brain Networks in Children With Autism and Typical Development
Lead Sponsor:
Children's Hospital of Fudan University
Collaborating Sponsors:
ShanghaiTech University
Conditions:
Autism Spectrum Disorder
Healthy
Eligibility:
All Genders
2-17 years
Brief Summary
The goal of this observational study is to compare the brain functional network between children with autism and typical development, using magnetic resonance imaging (MRI), electroencephalogram/event...
Detailed Description
The cross-sectional observational study will be performed to compare the differences of functional brain network and reactions to social stimulus between children with autism and typical development. ...
Eligibility Criteria
Inclusion
- Case group:
- Children diagnosed with ASD according to a clinical judgement based on the criteria of ASD in DSM-5 and further confirmed with ADOS-2;
- Ages 2-17 years;
- Parents/caregivers understand the content of the study and agree to participate in.
Exclusion
- Rett Syndrome, Fragile X Syndrome, Angelman Syndrome, Prader-Willi Syndrome, tuberous sclerosis, and other syndromes caused by known genetic defects or inherited metabolic diseases;
- Children with brain injuries, specific chronic or congenital diseases.
- The gestational age is less than 37 weeks, or the birth weight is lower than 2500g.
- Children cannot receive the head MRI examination.
- Control group:
- Inclusion Criteria:
- Healthy children age between 2 to 17 years.
- Children without the family history of ASD or other neurodevelopmental/mental diseases.
- Parents/caregivers understand the content of the study and agree to participate in.
Key Trial Info
Start Date :
April 7 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2029
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT06908174
Start Date
April 7 2025
End Date
July 1 2029
Last Update
May 29 2025
Active Locations (1)
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1
Children's Hospital of Fudan University
Shanghai, China