Status:
RECRUITING
Efficacy and Safety of Citrate Anticoagulation in CRRT for Patients With Liver Failure/DysfuncTION, the CAUTION Trial! A Retrospective Study on Etiology of Liver Failure and Their Complications
Lead Sponsor:
University Hospital, Antwerp
Conditions:
Liver Failure
AKI - Acute Kidney Injury
Eligibility:
All Genders
18+ years
Brief Summary
Study design A retrospective cohort study will be conducted to compare the efficacy and safety of citrate anticoagulation in CRRT among patients with liver failure/dysfunction and severe shock. Objec...
Detailed Description
Continuous renal replacement therapy (CRRT) is a crucial intervention for managing acute kidney injury (AKI) in critically ill patients. Citrate anticoagulation has become a preferred method in CRRT d...
Eligibility Criteria
Inclusion
- Critically ill patients diagnosed with AKI requiring CRRT. Caution Protocol V1.0 24-07-2024
- Documented liver failure or significant liver dysfunction (e.g., elevated liver enzymes, bilirubin levels, or clinical diagnosis of liver failure) and clincal diagnosis of shock (NE of 0.25 μg/kg/min and or association of second vasopressor).
- Age ≥ 18 years.
Exclusion
- NA
Key Trial Info
Start Date :
September 30 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06908746
Start Date
September 30 2024
End Date
December 31 2025
Last Update
April 3 2025
Active Locations (1)
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1
Antwerp University Hospital
Edegem, Antwerp, Belgium, 2650