Status:
ENROLLING_BY_INVITATION
Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty
Lead Sponsor:
Regionshospitalet Silkeborg
Conditions:
Total Knee Arthroplasty
Regional Anesthesia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This trial aims to assess the analgesic effect of Popliteal Plexus Block (PPB) with 10 mL versus 20 mL of Bupivacain 5 mg/mL, when applied as an adjunct treatment to a multimodal analgesic regimen fol...
Detailed Description
Patients will undergo primary unilateral total knee arthroplasty with insertion of non-cruciate retaining standard cemented prosthesis by a parapatellar medial approach, without use of tourniquet or L...
Eligibility Criteria
Inclusion
- Scheduled to undergo primary total knee arthroplasty in spinal anesthesia.
- Ability to give their written informed consent after having fully understood the contents of the study.
- American Society of Anesthesiologists (ASA) physical status 1, 2, or 3.
Exclusion
- Patients who cannot read or speak Danish.
- Patients who cannot operate or have access to a smartphone with internet connectivity (required for patient-reported outcome assessment).
- Patients with allergies or intolerance to the medicines used in the study.
- Patients with a consistent daily intake of opioids preoperatively.
- Patients who are dependent on walking aid devices preoperatively.
- Patients suffering from alcohol and/or drug abuse - based on the investigator's assessment.
- BMI \> 40.
- Diagnosed with chronic neurodegenerative disorders.
Key Trial Info
Start Date :
April 7 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT06908837
Start Date
April 7 2025
End Date
March 1 2026
Last Update
April 11 2025
Active Locations (1)
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1
Elective Surgery Centre at Silkeborg Regional Hospital
Silkeborg, Denmark Central Region, Denmark, 8600