Status:

COMPLETED

Effect of Intraarticular Ozone, Prolotherapy or Dexmedetomidine in Pain Limitation in Knee Osteoarthritis

Lead Sponsor:

Tanta University

Conditions:

Intraarticular

Ozone

Eligibility:

All Genders

30-65 years

Phase:

NA

Brief Summary

This study aimed to compare intraarticular ozone injection, prolotherapy, or dexmedetomidine effectiveness in knee osteoarthritis patients.

Detailed Description

Osteoarthritis (OA) is a heterogeneous group of disorders of different etiologies with similar biological, morphological, and clinical manifestations and outcomes. The intraarticular injection has bee...

Eligibility Criteria

Inclusion

  • Age from 30 to 65 years.
  • Both genders.
  • Patients diagnosed with stage 1-3 osteoarthritis according to the Kellgren-Lawrence Classification System (K-L).

Exclusion

  • Patient refusal.
  • History of knee trauma within the past month.
  • Rheumatic disease.
  • Pregnancy.
  • Any surgical intervention of the knee.
  • Severe cardiovascular disease.
  • Morbid obese patients (body mass index (BMI) of \>35 kg/m2).
  • Local infection at the site of injection.
  • Bleeding diathesis.

Key Trial Info

Start Date :

October 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2023

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06909305

Start Date

October 1 2022

End Date

October 1 2023

Last Update

April 3 2025

Active Locations (1)

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Tanta University

Tanta, El-Gharbia, Egypt, 31527