Status:
RECRUITING
Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation
Lead Sponsor:
ART Fertility Clinics LLC
Collaborating Sponsors:
Khalifa University for Science and Technology
New York University Abu Dhabi
Conditions:
Neural Activity
Brain Function
Eligibility:
FEMALE
25-35 years
Brief Summary
The investigators aim is to investigate the brain's dynamic complexity across three phases of an ovarian stimulation cycle (basal, pre-OPU, mid-luteal), to observe the impact of externally administere...
Detailed Description
The investigators seeks to fill a significant gap in our understanding of the impact of ovarian stimulation on brain dynamics, an area that has not been previously explored. By investigating the brain...
Eligibility Criteria
Inclusion
- Age group: 25 - 35 years old
- BMI: 20 - 30
- Anti-Mullerian Hormone (AMH): 1.3 - 5.9 ng/ml
- Regular Menstrual Cycle: 26-35 days
- In case of previous use of hormonal contraception: wash-out period of 3 month
- Meet standard safety and eligibility criteria for MRI scanning, including the absence of contraindications such as metallic implants, claustrophobia, or other medical conditions that preclude MRI
Exclusion
- History of ovarian surgery
- Pathology of the ovaries
- Mental health disorders
- Use of medication influencing brain function
- Ongoing use of hormonal contraception (this would include OCP, but also patches and Mirena containing IUD)
Key Trial Info
Start Date :
April 7 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 5 2026
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT06910293
Start Date
April 7 2025
End Date
December 5 2026
Last Update
June 10 2025
Active Locations (2)
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1
ART Fertility Clinics LLC
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates, 00000
2
ART Fertility Clinics LLC
Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates, 60202