Status:
RECRUITING
Impact of Aerobic Exercise on the Anticancer Immune Response in Patients Receiving Cancer Treatment
Lead Sponsor:
Université de Sherbrooke
Conditions:
Colorectal Cancer
Breast Cancer
Eligibility:
All Genders
40-70 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to determine to what extent anticancer immune cells mobilized by aerobic exercise exhibit migratory and functional capacity towards cancer cells in patients undergoi...
Detailed Description
In recent years, there has been growing interest in the therapeutic role of exercise in the context of oncology. Several murine models have demonstrated a reduction in tumor growth with aerobic exerci...
Eligibility Criteria
Inclusion
- Diagnosis of non-metastatic breast or colon cancer
- Age between 40 and 70
- Have started chemotherapy or immunotherapy treatment and have at least three treatments remaining in the cycle
- ECOG stage 0 to 1
- Be able to perform moderate-intensity aerobic exercise (MOD) or EPI type cycling according to the established prescription and without experiencing pain in connection with the bicycle saddle
Exclusion
- Orthopedic, cardiac or metabolic limitation preventing safe aerobic exercise
- Non-controlled health condition
- Use of beta-blockers
- Planned surgery during the study period.
Key Trial Info
Start Date :
April 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2027
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT06911970
Start Date
April 1 2025
End Date
September 30 2027
Last Update
August 29 2025
Active Locations (2)
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1
Research Center on Aging
Sherbrooke, Quebec, Canada, J1H 2J7
2
Research Center on Aging
Sherbrooke, Quebec, Canada, J1H 4C4