Status:

RECRUITING

Duration of Therapeutic Anticoagulation in Patients With Pulmonary Embolism

Lead Sponsor:

University Hospital, Strasbourg, France

Conditions:

Pulmonary Embolism

Eligibility:

All Genders

18+ years

Brief Summary

Current management of intermediate- and high-risk pulmonary embolism is primarily based on curative subcutaneous or intravenous anticoagulation, with or without systemic fibrinolytic therapy or thromb...

Eligibility Criteria

Inclusion

  • Adult patient (≥18 years old)
  • Hospitalized in the intensive care unit of Hautepierre Hospital (Strasbourg University Hospitals UF 6250) between January 1, 2014, and December 31, 2023
  • With a diagnosis of pulmonary embolism confirmed by a thoracic CT angiogram, a thoracoabdominopelvic CT scan, or a lung scan
  • Having received anticoagulation with curative-dose unfractionated heparin

Exclusion

  • Subjects who have expressed objection to the reuse of their data for scientific research purposes. - Patients diagnosed with pulmonary embolism prior to admission to the intensive care unit and for whom we cannot precisely determine the start date of anticoagulation (precision estimated to the nearest hour).
  • Pulmonary embolism not confirmed by contrast imaging (CT angiography)
  • Patients who have not received curative anticoagulation (contraindication)
  • Patients already receiving curative anticoagulation with UFH at the time of diagnosis
  • Patients with low-risk pulmonary embolism defined by an sPESI score of 0
  • Subject under court protection, guardianship, or curatorship

Key Trial Info

Start Date :

November 6 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06912009

Start Date

November 6 2024

End Date

December 31 2025

Last Update

December 17 2025

Active Locations (1)

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Service de Réanimation Médicale - CHU de Strasbourg - France

Strasbourg, France, 67091