Status:

RECRUITING

GWAS to Identify Predictive Genetic Factors for the Success of Dietary Intervention in the Treatment of IBS Symptoms

Lead Sponsor:

Attikon Hospital

Conditions:

Irritable Bowel Syndrome (IBS)

Genome-wide Association Study

Eligibility:

All Genders

18-65 years

Brief Summary

This is a GWAS that aims to identify possible single nucleotide polymorphisms (SNPs) that are associated with the response in a combined dietary pattern low in fermentable oligosaccharides, disacchari...

Detailed Description

Irritable bowel syndrome (IBS) is a very common chronic gastrointestinal disorder. Several factors seem to contribute to its development, such as psychological stress, intestinal dysbiosis, infections...

Eligibility Criteria

Inclusion

  • Fulfillment of the Rome IV criteria for IBS
  • Provision of written informed consent.
  • Commitment of availability throughout the study period.
  • IBS-SSS \> 175

Exclusion

  • Any concomitant disease requiring specialized nutrition (e.g. renal failure, diabetes, celiac disease, cerebrovascular disease of the central nervous system, major surgical cavity).
  • Pregnancy.
  • Breastfeeding.

Key Trial Info

Start Date :

September 15 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 15 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06912828

Start Date

September 15 2024

End Date

February 15 2027

Last Update

April 6 2025

Active Locations (1)

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Attikon General University Hospital of Athens

Athens, Greece, 12462