Status:
RECRUITING
Renal Perfusion and the Development of AKI Following Traumatic Injury
Lead Sponsor:
King's College Hospital NHS Trust
Conditions:
Traumatic Haemorrhagic Shock
AKI (Acute Kidney Injury) Due to Trauma
Eligibility:
All Genders
18+ years
Brief Summary
Acute kidney injury (AKI) is a complication of traumatic haemorrhagic shock (THS) and together these conditions increase mortality risk. Although septic shock patients who develop severe AKI are known...
Eligibility Criteria
Inclusion
- Age \> 18 years
- Within 24 hours of ICU admission following traumatic injury
- Received any blood products during initial resuscitation
- Lactate \> 2 mmol/l at any stage prior to study enrolment
Exclusion
- Known intolerance to Sonovue or any other ultrasound contrast agent
- Patients with un-survivable injuries / not expected to survive 24 hours in whom the intent of treatment is palliative
- Known CKD 4 or end stage renal failure
- Pregnancy
Key Trial Info
Start Date :
April 13 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06917053
Start Date
April 13 2024
End Date
July 1 2026
Last Update
April 8 2025
Active Locations (1)
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1
King's College Hospital
London, United Kingdom, SE5 9RS