Status:

RECRUITING

Roxadustat for Bone and Neuropsychiatric Aspects in Hemodialysis Patients

Lead Sponsor:

Mansoura University

Conditions:

Kidney Failure,Chronic

Anemia in End Stage Renal Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

People with severe kidney failure who need regular hemodialysis treatment often experience several health problems. These include anemia (low red blood cell count), issues with their bone health (some...

Detailed Description

Background: Chronic kidney disease (CKD) is a major global health issue. Renal anemia is a frequent and significant complication, affecting over 90% of patients with end-stage kidney disease (ESKD) r...

Eligibility Criteria

Inclusion

  • The age of the patient is more than 18.
  • Patients who are willing to sign informed consent.
  • Patients with ESKD on chronic hemodialysis for more than 3 months.

Exclusion

  • Current pregnancy or lactation.
  • Patients with pre-existing malignancy.
  • patients with psychosis.
  • Known history of hematological disorders or other causes of anemia other than CKD.
  • Taking medications that may significantly affect or interact with bone metabolism such as osteo-anabolics or bone resorptives during the last 6 months.

Key Trial Info

Start Date :

April 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2025

Estimated Enrollment :

46 Patients enrolled

Trial Details

Trial ID

NCT06917950

Start Date

April 15 2025

End Date

November 1 2025

Last Update

May 11 2025

Active Locations (1)

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1

Urology and Nephrology Center, Mansoura University

Al Mansurah, Dakahliya, Egypt, 35111