Status:
RECRUITING
Changes in the Urinary Microbiome and Metabolome During Treatment of the Overactive Bladder in Female Patients
Lead Sponsor:
University Hospital Ostrava
Collaborating Sponsors:
University Hospital Bulovka
Thomayer University Hospital
Conditions:
Overactive Bladder
Eligibility:
FEMALE
18+ years
Brief Summary
This is a non-interventional study that will not pose any burden for the participants. The study subjects will be examined and treated in a standard manner according to current clinical recommendation...
Detailed Description
Participation in the study will be offered to female patients who seek treatment for OAB symptoms themselves or are referred to centers participating in the project if a clinical diagnosis of idiopath...
Eligibility Criteria
Inclusion
- Adult women over 18 years of age
- Written consent to participate in the study
- Willingness to undergo OAB evaluation and treatment according to the protocol
- OAB symptoms lasting longer than 3 months
- At least 3 episodes of severe urgency with or without urge incontinence within 3 days documented by voiding diary
- OAB symptom score V8 questionnaire ≥ 8
Exclusion
- Known congenital developmental defects of the urinary tract (congenital hydronephrosis, vesicoureteral reflux, renal agenesis and hypoplasia, multicystic and polycystic kidneys)
- Any previous treatment for OAB
- Recurrent urinary tract infections (more than 3 episodes in the last 12 months)
- Presence of a foreign body in the urinary tract - urolithiasis, urinary catheter, ureteral stent
- Acute or chronic diseases with possible influence on the function of the lower urinary tract (LUT)
- Rheumatoid arthritis
- Diabetes mellitus
Key Trial Info
Start Date :
May 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06921746
Start Date
May 1 2025
End Date
December 31 2027
Last Update
May 4 2025
Active Locations (4)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Ostrava
Ostrava, Moravian-Silesian Region, Czechia, 70852
2
Thomayer University Hospital
Prague, Czechia, 14059
3
Institute of Microbiology of the Czech Academy of Sciences
Prague, Czechia, 14200
4
University Hospital Bulovka
Prague, Czechia, 18081