Status:
RECRUITING
The Biomechanical Outcomes of Autologous Chondrocyte Implantation
Lead Sponsor:
University of Manchester
Conditions:
Chondral Defect
Eligibility:
All Genders
18+ years
Brief Summary
Injury to the knee can damage the lining of the knee's bones, called cartilage. Cartilage injuries cause pain and limit movement, making activities like walking, playing sports, and working difficult....
Detailed Description
Knee joint articular cartilage is a primary load-bearing surface that endures repetitive high impact loading during activities of daily living. Individuals of any age can injure the knee's articular c...
Eligibility Criteria
Inclusion
- Diagnosis of a chondral injury to the knee by a consultant orthopaedic surgeon Participants must have this diagnosis, else they are not eligible for ACI surgery.
- Listed for ACI for a chondral injury by a consultant orthopaedic surgeon Participants must be listed for ACI, as this is the treatment of interest in this research study
- Over 18 years old Participants must be legally capable of providing informed consent for the study.
Exclusion
- Listed for any treatment other than ACI Participants must be listed for ACI, as this is the treatment of interest in this research study
- Under 18 years old. Participants must be legally capable of providing informed consent for the study.
Key Trial Info
Start Date :
April 22 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 8 2026
Estimated Enrollment :
47 Patients enrolled
Trial Details
Trial ID
NCT06921889
Start Date
April 22 2024
End Date
January 8 2026
Last Update
April 10 2025
Active Locations (7)
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1
Royal Orthopaedic Hospital
Birmingham, United Kingdom, B31 2AP
2
Addenbrooke's Hospital
Cambridge, United Kingdom, CB2 0QQ
3
Chapel Allerton Orthopaedic Centre
Leeds, United Kingdom, LS7 4SA
4
Trafford General Hospital
Manchester, United Kingdom, M415SL