Status:
RECRUITING
Tickle Stimulation in Disorders of Consciousness (DoC)
Lead Sponsor:
Anna Estraneo
Conditions:
Disorders of Consciousness
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this project is to investigate whether tickling stimulations can have a short-term effect on the responsiveness of patients with Disorders of Consciousness due to Severe Acquired Brain Inju...
Detailed Description
During the experimental session, patients will undergo the CRS-R and the Nociception Coma Scale-Revised (NCS-R) to ensure that any responses to tickling are not influenced by pain sensations. Subseque...
Eligibility Criteria
Inclusion
- Diagnosis of disorders of consciousness (DoC) based on the CRS-R scale;
- Age ≥18 years;
- Time since the event ≥ 28 days
Exclusion
- Large craniectomy that may interfere with fNIRS recording; Unstable clinical conditions (e.g., respiratory failure, fever, status epilepticus, etc.);
- Fractures, paralysis, injuries, or muscular dystrophy that prevent proper stimulation of the aforementioned body parts;
- Lack of informed consent from the legal representative.
Key Trial Info
Start Date :
June 30 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 31 2025
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT06922162
Start Date
June 30 2023
End Date
October 31 2025
Last Update
April 23 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Coma Science Group - University of Liege
Liège, Belgium, Belgium, 4000
2
Fondazione Don Gnocchi
Sant'Angelo dei Lombardi, Avellino, Italy, 83054