Status:
RECRUITING
Comparison of Skin Prick Testing, Extract-specific IgE Antibody Testing and Component Resolved Diagnosis in Diagnosing of Legume Allergy
Lead Sponsor:
University Hospital Pilsen
Collaborating Sponsors:
MacroArray Diagnostics GmbH
Conditions:
Food Allergy Suspected
Eligibility:
All Genders
4-65 years
Brief Summary
The study is aimed at improving the diagnosis of food allergy, specifically allergy to commonly consumed legumes such as peas, lentils, chickpeas or green beans. Patients suspected of allergy to these...
Detailed Description
Legumes are one of the major food allergens, but these are usually peanuts or soybeans. Other legumes, such as peas, lentils, chickpeas or green beans, have been overlooked, but some studies suggest t...
Eligibility Criteria
Inclusion
- age: ≤ 65 years
- signing informed consent to the study
- a positive history of an immediate allergic reaction to one or more of the legumes studied (peas, lentils, chickpeas, beans) with skin, gastrointestinal, respiratory or cardiovascular symptoms occurring within 2 hours after ingestion and a positive result of specific IgE testing against ALEX and/or skin prick test with the legume
- patients with a positive OFC with any of the legumes studied
Exclusion
- disagreement with the implementation of the oral food challenge
- history of severe systemic allergic reaction to the legume in question (Ring-Messmer grade ≥ 3)
Key Trial Info
Start Date :
October 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 31 2029
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06923878
Start Date
October 1 2023
End Date
March 31 2029
Last Update
April 11 2025
Active Locations (1)
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1
University Hospital Pilsen
Pilsen, Czech Republic, Czechia, 30100