Status:
NOT_YET_RECRUITING
Exosome-based Recurrence Score for Post-Treatment Ovarian Cancer
Lead Sponsor:
Fudan University
Conditions:
Ovarian Cancer
Eligibility:
FEMALE
18+ years
Brief Summary
The goal of this observational study is to develop an exosome-based scoring model for post-treatment surveillance of recurrence in ovarian cancer. The main questions it aims to answer are: 1. Does th...
Detailed Description
Ovarian cancer is the most lethal gynecologic malignancy with the lowest survival rate among the three major gynecological malignancies. Over 70% of ovarian cancer patients experience recurrence withi...
Eligibility Criteria
Inclusion
- Women aged ≥ 18 years
- Pathologic confirmed stage I-IV epithelial ovarian cancer, with ≤2 prior lines of therapy (maintenance therapy is not counted as a line of treatment), platinum-sensitive recurrence (achieved complete/partial response \[CR/PR\] after last platinum-based chemotherapy, with a platinum-free interval \>6 months), and radiologically confirmed recurrent disease
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
- A life expectancy of at least 6 months
- Written informed consent
Exclusion
- Patients with non-epithelial tumors
- Patients with history of other malignancies within the past 5 years (except completely resected basal cell carcinoma or squamous cell carcinoma of the skin)
- Women who are pregnant, lactating, or intend to become pregnant during the study period
- Patients who refuse to participate in the study
Key Trial Info
Start Date :
June 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06925126
Start Date
June 1 2025
End Date
December 31 2027
Last Update
April 13 2025
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