Status:
COMPLETED
The Effect of Hypotensive Anesthesia on Cognitive Functions in Orthognatic Surgery
Lead Sponsor:
Medipol University
Conditions:
Cognitive Dysfunction
Postoperative Complications
Eligibility:
All Genders
18-50 years
Brief Summary
The purpose of this study is to evaluate the effects of maintaining adequate cerebral oxygen saturation on patients undergoing orthognathic surgery. Orthognathic surgery is performed to repair anomali...
Detailed Description
Orthognathic surgery is a surgical procedure performed to repair anomalies in the maxillofacial skeleton. It can be performed for maxillofacial aesthetics as well as for functional purposes. Since ort...
Eligibility Criteria
Inclusion
- Patients undergoing Orthognathic surgery under general anesthesia ASA grade ≤ grade III; Patients can communicate normally, can cooperate and complete cognitive function test; Patients volunteered and signed informed consent.
Exclusion
- BMI \< 18 or \> 27 kg / m2; Previous history of dementia, psychosis or other central nervous system diseases or mental diseases, such as cerebral infarction, stroke, Parkinson's disease, etc; Patients taking sedatives or antidepressants; Alcoholics or drug addicts; Patients with cognitive impairment before operation (MMSE score \< 23); Patients with peripheral vascular diseases and contraindication of arterial puncture and catheterization; Patients unable to carry out long-term follow-up or poor compliance.
Key Trial Info
Start Date :
December 19 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 19 2024
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT06925711
Start Date
December 19 2022
End Date
February 19 2024
Last Update
April 13 2025
Active Locations (1)
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1
Istanbul Medipol University Hospital
Istanbul, Turkey (Türkiye), 34070