Status:
RECRUITING
Safety, Efficacy, and Survival Outcomes of Neoadjuvant/Induction Immunotherapy in Surgical and Radiotherapeutic Management of Non-Small Cell Lung Cancer
Lead Sponsor:
Peking University Cancer Hospital & Institute
Conditions:
Lung Cancer (NSCLC)
Neoadjuvant Immunotherapy
Eligibility:
All Genders
18+ years
Brief Summary
This multicenter retrospective real-world study aims to evaluate the safety, efficacy and survival outcomes of neoadjuvant/induction immunotherapy in patients with non-small cell lung cancer (NSCLC). ...
Detailed Description
Lung cancer is the leading cause of cancer-related deaths in both China and the world. In recent years, neoadjuvant immunotherapy has achieved breakthrough advancements in the treatment of non-small c...
Eligibility Criteria
Inclusion
- Histologically confirmed non-small cell lung cancer (NSCLC), regardless of the presence of EGFR or ALK sensitive driver gene mutations;
- Clinical staging of IA-IIIC according to the AJCC 8th Edition before neoadjuvant treatment;
- Received at least one cycle of neoadjuvant immunotherapy (with or without chemotherapy);
- Assessed as resectable or potentially resectable by surgical experts prior to treatment.
Exclusion
- Confirmed M1 disease;
- History of previous lung malignancy or other metastatic malignant tumors;
- Participation in other randomized controlled trials involving neoadjuvant treatment;
- Significant missing clinical data.
Key Trial Info
Start Date :
December 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 31 2028
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT06926179
Start Date
December 1 2024
End Date
March 31 2028
Last Update
April 16 2025
Active Locations (4)
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1
Peking University Cancer Hospital & Institute
Beijing, Beijing Municipality, China, 100142
2
Peking University Third Hospital
Beijing, Beijing Municipality, China
3
Inner Mongolia Hospital of Peking University Cancer Hospital
Hohhot, Inner Mongolia, China
4
The Third Affliated Hospital of Kunming Medical University
Kunming, Yunnan, China