Status:

ENROLLING_BY_INVITATION

Intraocular Gas Tamponade for Treatment of Large Idiopathic Macular Holes

Lead Sponsor:

The Filatov Institute of Eye Diseases and Tissue Therapy

Collaborating Sponsors:

Ukrainian Vitreoretinal Society

Conditions:

Idiopathic Macular Hole

Macular Hole

Eligibility:

All Genders

50-90 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to evaluate the visual and anatomical outcomes of large (410-1000 μm) full-thickness macular holes repair surgery using perfluoropropane (15% C3F8), sulfur hexafluor...

Detailed Description

The project is a randomized clinical trial with a follow up time of 6 months comparing the effects of surgical treatment of large (410-1000 μm) idiopathic macular holes. Patients are randomized to vit...

Eligibility Criteria

Inclusion

  • Patient age 50 or above.
  • Duration of Symptoms ≤ 12 months.
  • Macular holes having a diameter 410-1000 μm.
  • Informed consent.

Exclusion

  • Patients under 50 years of age.
  • A patient who has already undergone treatment (surgery, laser etc.) for any disease of the retina.
  • Traumatic or pediatric macular holes, and associated retinal detachment.
  • History of any retinal disease such as high myopia, retinal dystrophies, central serous retinopathy, retinal vascular diseases, diabetic retinopathy, uveitis etc.
  • Previous history of glaucoma or ocular hypertension.
  • Failure to give informed consent.

Key Trial Info

Start Date :

February 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06927544

Start Date

February 1 2025

End Date

February 1 2027

Last Update

April 17 2025

Active Locations (1)

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The Filatov Institute of Eye Diseases and Tissue Therapy

Odesa, Ukraine, 65061