Status:

ENROLLING_BY_INVITATION

Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients

Lead Sponsor:

Tanta University

Conditions:

Hypertension

Eligibility:

All Genders

Up to 70 years

Phase:

NA

Brief Summary

Pain control in dentistry is an important factor for reducing the fear and anxiety associated with dental procedures. For tooth extraction, it is mandatory to use resources to manage pain and discomfo...

Detailed Description

The aim of this prospective study is to compare the anesthetic efficacy and hemodynamic parameters of 4% articaine chloridrate with epinephrine (1:100,000) versus 3% mepivacaine chloridrate without ep...

Eligibility Criteria

Inclusion

  • patients in need of single tooth extraction owing to caries and/or periodontitis in the maxilla, with controlled hypertension with blood pressure not exceeding values of 160/100 mm Hg

Exclusion

  • patients with systemic health problems (e.g uncontrolled hypertension, unstable angina pectoris
  • recent myocardial infarct (6 months)
  • refractory dysrhythmias
  • untreated or uncontrolled congestive heart failure)
  • uncontrolled diabetes mellitus
  • history of allergic reactions to anesthetics drugs
  • Pregnancy or breastfeeding
  • Patients requiring open surgical extractions or with infected teeth

Key Trial Info

Start Date :

January 10 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 10 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06927726

Start Date

January 10 2025

End Date

December 10 2025

Last Update

November 18 2025

Active Locations (1)

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faculty of dentistry, Tanta university

Tanta, Tanta, Egypt, 31111