Status:
COMPLETED
Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction
Lead Sponsor:
Duke University
Conditions:
Chest Pain
Shortness of Breath
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
The purpose of this study is to find out if additional images taken during a stress echocardiogram study and risk score calculation will help the doctor determine if shortness of breath or chest pain ...
Eligibility Criteria
Inclusion
- Clinically indicated exercise stress echo for the evaluation of exertional dyspnea or chest pain
- Age ≥50 years
Exclusion
- Known history of HFpEF
- LVEF \<50% on baseline echo study
- History of hypertrophic cardiomyopathy, amyloidosis, or pulmonary arterial hypertension, severe right ventricular dysfunction and severe valvular disease based on chart review or baseline echo study
- History of organ transplant (heart, kidney, liver, lungs)
- Severe pulmonary disease requiring ambulatory oxygen therapy
- End-stage renal disease requiring long-term renal replacement therapy
- Decompensated liver disease
- Conditions that prevent accurate assessment of E/e' ratio (mitral prosthetic valve, severe mitral annular calcification)
- Plan to use echo contrast agent during stress study (i.e. contrast agent needed for baseline study)
- Patients from outside Duke health system with no plan for long-term care at Duke
Key Trial Info
Start Date :
May 30 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 19 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06927973
Start Date
May 30 2025
End Date
December 19 2025
Last Update
December 23 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Duke University Medical Center
Durham, North Carolina, United States, 27710