Status:
COMPLETED
Estrogen and Propofol Injection Pain
Lead Sponsor:
Konya City Hospital
Conditions:
Pain
Estradiol
Eligibility:
FEMALE
18-45 years
Brief Summary
This prospective observational study investigates the relationship between serum estrogen concentration and the incidence and severity of propofol injection pain (PIP) in female patients undergoing ge...
Detailed Description
This prospective observational study aims to evaluate the association between serum estrogen levels and the incidence and severity of propofol injection pain (PIP) in adult female patients undergoing ...
Eligibility Criteria
Inclusion
- Female patients aged between 18 and 45 years
- American Society of Anesthesiologists (ASA) physical status I or II
- Scheduled for surgery under general anesthesia
- Availability of a preoperative serum estradiol (E2) level
- For Group 1: Undergoing IVF procedure with supraphysiological E2 levels (\>350 pg/mL)
- For Group 2: Undergoing elective surgery with normal E2 levels (15-350 pg/mL)
Exclusion
- ASA physical status III or IV
- Pregnant patients
- Perimenopausal women
- Male patients
- Patients younger than 18 or older than 45 years
- History of psychiatric disorders
- Patients undergoing emergency surgery
Key Trial Info
Start Date :
May 2 2025
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 10 2025
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06929416
Start Date
May 2 2025
End Date
September 10 2025
Last Update
September 16 2025
Active Locations (1)
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1
Konya City Hospital
Konya, Turkey (Türkiye), 42020