Status:
NOT_YET_RECRUITING
Muscular Synergies and Behavioral Adaptations of Gait in Pain Anticipation (SYAMAPP)
Lead Sponsor:
Universite de Picardie Jules Verne
Conditions:
Nocebo Effect
Pain Anticipation
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether the anticipation of pain influences gait control and psychophysiological responses in healthy individuals. Participants will receive a neutral cream d...
Detailed Description
Pain anticipation can significantly alter motor behavior and physiological responses, even in the absence of actual pain. While previous research has established that conditioned expectations can modi...
Eligibility Criteria
Inclusion
- Aged 18-35 years
- Healthy participant with no self-reported diagnosed neurological, musculoskeletal, or cardiovascular disorders
- Body Mass Index (BMI) \< 30
- Ability to walk unaided for at least 10 minutes without major physical limitations
Exclusion
- Presence of pain at the time of testing
- Self-reported diagnosed condition affecting mobility
- Known allergy to any component of the study cream
- Allergy to EMG electrode adhesives
- Inability to stand unassisted for more than 1 minute
- Inability to walk/run at the required speed and distance
- Weight exceeding 150 kg (due to treadmill limitations)
- Recent intake of:
- Analgesics (within 6 hours)
- Cigarettes (within 6 hours)
- Caffeine (within 2 hours)
- Skin lesions at the cream application site
- Pregnancy
- Failure to understand instructions
- Daytime pain reported by participant on day of experimentation
Key Trial Info
Start Date :
October 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 30 2028
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT06929559
Start Date
October 1 2025
End Date
October 30 2028
Last Update
September 26 2025
Active Locations (1)
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1
Université de Picardie Jules Verne
Amiens, France