Status:
TERMINATED
Genicular Artery Embolization (GAE) vs inTra-articular Corticosteroid Injection for Osteoarthritic Knee Pain.
Lead Sponsor:
National Taiwan University Hospital
Collaborating Sponsors:
National Taiwan University Hospital, Yun-Lin Branch
Conditions:
Osteoarthritis (OA) of the Knee
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
This study investigates genicular artery embolization (GAE) as a minimally invasive alternative to ntra-articular corticosteroid injections (IA) or treating knee osteoarthritis (OA) pain. Designed as ...
Eligibility Criteria
Inclusion
- Age ≥ 40 years
- Symptomatic knee pain, with numeric rating scale (NRS) ≥ 4.
- Insufficient or resistant to conservative treatment, including oral analgesics, physical therapy, intra-articular injections for at least 3 months, before the enrollment.
- Weight bearing X ray of knee: osteoarthritis of Kellgren-Lawrence grade 1, 2, or 3.
Exclusion
- History of trauma in recent 6 months.
- Bleeding tendency.
- Poor renal function (serum creatinine \> 2.0 mg/dL).
- Pregnancy or breast-feeding.
- Severe peripheral arterial occlusive disease (PAOD).
- Local infections or inflammatory arthritis of knee.
- Rheumatoid arthritis or other rheumatological diseases.
- Prior knee surgeries (arthroscopic surgery, menisci repair, cruciate ligament reconstruction, arthroplasty of knee) due to knee pain.
- Malignancy
- ECOG \> grade 2
- Life expectancy less than 2 years.
- Any other condition related to the patient's health, regarded exclusionary in the opinion of the investigator.
Key Trial Info
Start Date :
March 25 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 2 2025
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT06929585
Start Date
March 25 2025
End Date
October 2 2025
Last Update
November 19 2025
Active Locations (1)
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1
National Taiwan University Hosiptal Yunlin Branch
Douliu, Yunlin, Taiwan, 640