Status:
RECRUITING
Multi-Center Clinical Trial of Shenling Baizhu Granules for Preventing Low-Risk Colorectal Adenoma Recurrence
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Low-risk Colorectal Adenoma
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
The goal of this clinical trial is to learn if Shenling Baizhu granules can prevent colorectal adenoma from coming back in people who had low-risk colorectal adenomas removed. The main questions it ai...
Eligibility Criteria
Inclusion
- Diagnosed with low-risk colorectal adenoma
- Complete colonoscopy examination (adequate bowel preparation, cecal intubation, withdrawal time \>6 minutes), with endoscopic resection performed including snare polypectomy, EMR, EPMR, ESD
- Within 1 month after adenoma resection
- Age 18-70 years
- Willing to provide written informed consent
Exclusion
- Incomplete adenoma resection
- Long-term use of aspirin, folic acid, calcium, or vitamin D supplements
- Familial adenomatous polyposis, hereditary non-polyposis colorectal cancer (Lynch syndrome), or other hereditary polyposis syndromes
- Severe inflammatory bowel disease
- History of malignancy within past 5 years (excluding basal cell carcinoma of the skin and/or cervical intraepithelial neoplasia after surgery)
- Pregnant or lactating women
- Severe cardiovascular disease, cerebrovascular disease, liver or kidney dysfunction, or diabetes
- Severe mental illness that prevents compliance with colonoscopy examination
Key Trial Info
Start Date :
November 21 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2028
Estimated Enrollment :
624 Patients enrolled
Trial Details
Trial ID
NCT06930157
Start Date
November 21 2025
End Date
December 31 2028
Last Update
December 4 2025
Active Locations (1)
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1
Renji Hospital
Shanghai, Shanghai Municipality, China