Status:
NOT_YET_RECRUITING
Mindfulness-Enhanced Dual-Task Training in PD-MCI
Lead Sponsor:
Nanjing Mingzhou Rehabilitation Hospital
Conditions:
Mild Cognitive Impairment (MCI)
Parkinson's Disease (PD)
Eligibility:
All Genders
55-75 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if Mindfulness-Enhanced Dual-Task Training work to treat PD-MCI in adults. The main questions it aims to answer are: Does Mindfulness-Enhanced Dual-Task Tr...
Eligibility Criteria
Inclusion
- Age: Between 55 and 75 years.
- Disease Diagnosis: Clinically diagnosed with Idiopathic Parkinson's Disease (PD) according to the UK Parkinson's Disease Society Brain Bank Criteria.
- Disease Stage: Hoehn \& Yahr (H\&Y) stages 1 to 2.5.
- Cognitive Function: Montreal Cognitive Assessment (MoCA) score between 23 and 26, indicating mild cognitive impairment (MCI).
- Medication Stability: Stable doses of antiparkinsonian medications for at least 4 weeks prior to screening.
- Subjective Cognitive Complaints: Self-reported or informant-reported cognitive decline persisting for at least 6 months.
- Ambulatory Ability: Able to walk independently, with or without assistive devices.
- Sensory Abilities: Adequate vision and hearing to comply with study procedures.
- Informed Consent: Willingness to provide written informed consent and comply with study requirements.
Exclusion
- Other Neurological Disorders: Presence of other neurological conditions that could affect cognitive function, such as Alzheimer's disease, stroke, or brain tumors.
- Psychiatric Conditions: Severe psychiatric disorders, including major depressive disorder or schizophrenia.
- Substance Abuse: Recent history of drug or alcohol abuse.
- Serious Medical Conditions: Uncontrolled hypertension, diabetes, heart disease, or other conditions that could interfere with study participation or outcomes.
- Severe Cognitive Impairment: Diagnosis of Parkinson's Disease Dementia (PDD).
- Other Factors Affecting Cognition: Recent head trauma, uncontrolled thyroid dysfunction, vitamin B12 deficiency, or other conditions known to affect cognitive function.
- Deep Brain Stimulation (DBS): History of DBS treatment. Participation in Other Clinical Trials: Participation in another clinical trial that could interfere with this study within the last 3 months.
Key Trial Info
Start Date :
May 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 30 2025
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT06930742
Start Date
May 1 2025
End Date
July 30 2025
Last Update
April 16 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Nanjing Mingzhou Rehabilitation Hospital
Nanjing, Jiangsu, China, 210046