Status:

COMPLETED

Effect of the Anticholinergic Drug Burden on Postoperative Delirium in Elderly Chinese Patients: A Nested Case-Control Study

Lead Sponsor:

Hao Li

Conditions:

Delirium - Postoperative

Eligibility:

All Genders

65-90 years

Brief Summary

This study aims to investigate the association between preoperative anticholinergic drugs burden and postoperative delirium in elderly Chinese patients.

Eligibility Criteria

Inclusion

  • patients over 65 years; Undergoing general anesthesia; Inpatients who had surgery between Aprill 1, 2020 and Aprill 1, 2022.

Exclusion

  • ASA grade V; preoperative Mini-Mental State Examination (MMSE) score \<24;history of neurological disorders (such as cerebrovascular disease or dementia); emergency surgeries; operative duration ≤30 minutes, and cases with \>5% missing data.

Key Trial Info

Start Date :

April 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2022

Estimated Enrollment :

10536 Patients enrolled

Trial Details

Trial ID

NCT06931353

Start Date

April 1 2020

End Date

April 1 2022

Last Update

April 17 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

First Medical Center of Chinese PLA General Hospital

Beijing, China