Status:
NOT_YET_RECRUITING
Ozone Reaction Products and Skin Health
Lead Sponsor:
Fudan University
Conditions:
Skin Health
Eligibility:
All Genders
18-30 years
Phase:
NA
Brief Summary
This is a randomized controlled human exposure study. Investigators aim to investigate the products of ozone-sebum reactions and their acute effects on skin health of healthy young adults.
Detailed Description
The investigators will conduct a randomized, controlled human exposure study involving 40 healthy young adults in Shanghai, China. Each participant will have both forearms simultaneously exposed-one i...
Eligibility Criteria
Inclusion
- Living in Shanghai during the study period;
- Having healthy skin conditions on both forearms.
Exclusion
- Subjects with a history of smoking and alcohol abuse;
- Subjects with a regular use of medication and dietary supplements within 2 months prior to enrollment;
- Subjects with severe skin diseases, such as atopic dermatitis, eczema, or severe acne;
- Subjects with allergic diseases, such as allergic rhinitis, allergic asthma, or atopy, or history of allergic reactions within 2 months prior to enrollment;
- Subjects with cardiovascular diseases, such as congenital heart disease, pulmonary heart disease, or hypertension;
- Subjects with respiratory diseases, such as asthma, acute or chronic bronchitis, or pneumonia;
- Subjects with chronic diseases, such as diabetes, chronic hepatitis, or kidney disease;
- Subjects with cutaneous abnormalities on forearm, such as severe pigmentation, multiple nevus, or tattooing;
- Subjects who underwent cosmetic intervention on forearms within 2 months prior to enrollment, such as whitening treatments, UV exposure therapies, depigmentation procedures, or tanning;
- Females in pregnancy or lactation status.
Key Trial Info
Start Date :
April 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06932419
Start Date
April 1 2025
End Date
December 1 2026
Last Update
April 17 2025
Active Locations (1)
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1
Department of Environmental Health, School of Public Health, Fudan University
Shanghai, Shanghai Municipality, China, 200032