Status:
RECRUITING
The BRAINMAP-DBS Study: BRain Network AnalysIs usiNg 7-Tesla MRI and MAgnetoencephalograPhy for Deep Brain Stimulation
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions:
Deep Brain Stimulation
Parkinson Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Rationale: Deep brain stimulation (DBS) is an effective treatment for essential tremor and Parkinson's disease. The effect of DBS relies on the modulation of dysfunctional motor brain networks and on ...
Detailed Description
Deep brain stimulation for Parkinson's disease and essential tremor The effect of deep brain stimulation (DBS) relies on the modulation of dysfunctional motor brain networks.1,2 On average, 50% motor ...
Eligibility Criteria
Inclusion
- In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- Age \> 18 years;
- Idiopathic PD/ET with at least six months of DBS
- Underwent a preoperative 7-Tesla MRI scan
Exclusion
- A potential subject who meets any of the following criteria will be excluded from participation in this study:
- Legally incompetent adults;
- No written informed consent.
- A spinal stimulation or deep brain stimulation system is not compatible with 7-Tesla MRI
- There a no implants inadmissible in the MEG, although patients will be questioned for possible (non-removable) implants such as pacemakerand/or dental as they may interfere with the magnetic signals
Key Trial Info
Start Date :
April 23 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2035
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT06932692
Start Date
April 23 2024
End Date
December 31 2035
Last Update
April 17 2025
Active Locations (1)
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1
Amsterdam UMC
Amsterdam, North Holland, Netherlands, 1011AZ