Status:
COMPLETED
Evaluation of Wnt5a and LRP5 Levels in Serum and Saliva Samples and the Relationship Between Clinical Periodontal Parameters
Lead Sponsor:
Ankara University
Collaborating Sponsors:
The Scientific and Technological Research Council of Turkey
Conditions:
Periodontal Disease
Periodontitis (Stage 3)
Eligibility:
All Genders
18-70 years
Brief Summary
Objectives: Wnt5a is a secreted Wnt ligand that plays an important role in cellular homeostasis. Wnt interaction with coreceptor low-density lipoprotein receptor-related protein 5 (LRP5) induces the p...
Eligibility Criteria
Inclusion
- \>18 years old,
- At least 16 permanent teeth except 3rd molars,
- Individuals who do not use orthodontic appliances,
- Individuals who are not pregnant or lactating,
- Individuals without any systemic disease that may affect periodontal health,
- Systemically healthy individuals,
- Individuals who have not used anti-inflammatory and/or anti-microbial drugs in the last 6 months,
- Individuals who have not received periodontal treatment in the last 1 year
Exclusion
- Pregnant/lactating individuals,
- Individuals who have used anti-inflammatory and/or anti-microbial drugs in the last 6 months,
- Individuals who have undergone periodontal treatment in the last 1 year,
- Individuals with psychiatric illness,
- Individuals with any oral infection,
- Individuals with \<16 teeth, excluding molars,
- Individuals with alcohol dependence,
- Individuals with active infectious disease (acute hepatitis, AIDS, tuberculosis), cancer or any systemic condition that may affect periodontal tissues,
- Individuals receiving treatment with drugs known to affect periodontal tissues (phenytoin, cyclosporine A, calcium channel blockers)
Key Trial Info
Start Date :
April 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2025
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06933784
Start Date
April 1 2024
End Date
March 1 2025
Last Update
April 18 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ankara University, Faculty of Dentistry
Ankara, Yenimahalle, Turkey (Türkiye), 06500