Status:
RECRUITING
Revised Targets for Knee Radiofrequency Ablation
Lead Sponsor:
Centro Hospitalar Universitario do Algarve
Conditions:
Osteoarthritis Knee Pain
Eligibility:
All Genders
18+ years
Brief Summary
This research team is doing a study to learn more about a new way to treat long-term knee pain caused by joint damage. They are using a treatment called radiofrequency ablation (RFA). This is a proced...
Detailed Description
This study applies a modified ultrasound-guided radiofrequency ablation (RFA) protocol for targeting the genicular nerves, informed by recent anatomical research. Conventional genicular nerve RFA tech...
Eligibility Criteria
Inclusion
- Patients with chronic knee pain related to radiographic knee osteoarthritis, Kellgren-Lawrence (KL) grade III or IV, who are refractory to conservative treatment.
- (Refractoriness to conservative treatment is defined as:
- Persistent pain and functional limitation after undergoing knee-targeted physiotherapy and analgesic medication in accordance with clinical guidelines for osteoarthritis \[e.g., paracetamol, nonsteroidal anti-inflammatory drugs, and other drugs as deemed appropriate by the treating physician\];
- Persistent pain and functional limitation after intra-articular corticosteroid injections or limited success with such interventions.)
Exclusion
- Patients with previous knee arthroplasty
- Patients who have undergone prior radiofrequency (RF) ablation
- Significant psycho-emotional disorders
- Addictive behaviors
- Generalized pain
- Nociplastic pain
- Presence of a pacemaker
- Presence of osteosynthesis material in the knee or adjacent anatomical regions
Key Trial Info
Start Date :
March 20 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 30 2031
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06934421
Start Date
March 20 2025
End Date
July 30 2031
Last Update
April 24 2025
Active Locations (2)
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1
Serviço de Medicina Física e de Reabilitação - Hospital de Faro - Unidade Local de Saúde do Algarve
Faro, Portugal, 8000-386
2
Serviço de Medicina Física e de Reabilitação - Hospital de São Francisco Xavier - Unidade Local de Saúde de Lisboa Ocidental
Lisbon, Portugal, 1449-005