Status:
RECRUITING
Replication of the Heads Up Atopic Dermatitis Trial With Registry Data
Lead Sponsor:
Technische Universität Dresden
Conditions:
Atopic Dermatitis
Eligibility:
All Genders
18+ years
Brief Summary
The goal is the replication of the primary outcome (EASI 75 at week 16) of the Heads Up trial (Blauvelt, A, Teixeira, H, Simpson, E et al (2021) doi:10.1001/jamadermatol.2021.3023) and the evaluation ...
Detailed Description
Atopic dermatitis (AD) is an inflammatory, multifactorial skin disease characterized by eczematous skin lesions, severe itching, and negative consequences on quality of life. The goal of this study is...
Eligibility Criteria
Inclusion
- Chronic AD with onset of symptoms at least 3 years prior to baseline
- Meets UK working party criteria
- EASI score ≥ 16
- ≥ 10% body surface area (BSA) of AD involvement at baseline ("therapy start") visit
Exclusion
- contraindications according to upadacitinib or dupilumab labeling
Key Trial Info
Start Date :
August 2 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT06937788
Start Date
August 2 2021
End Date
December 31 2025
Last Update
August 21 2025
Active Locations (1)
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1
Center for Evidence Based Health Care
Dresden, Saxony, Germany, 01307