Status:
RECRUITING
Optimised Decrement Evoked Potential (DeEP) Mapping to Guide Ventricular Tachycardia (VT) Ablation in Patients With Structural Heart Disease VT
Lead Sponsor:
University Hospitals Coventry and Warwickshire NHS Trust
Conditions:
Structural Heart Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Ventricular tachycardia (VT) is a life-threatening heart rhythm disorder. Special pacemakers called implantable cardiac defibrillators (ICDs) help treat VT episodes, however they do not prevent the VT...
Eligibility Criteria
Inclusion
- ≥18 years old
- Patients with an implantable cardioverter defibrillator (ICD)
- Eligible for VT ablation as part of standard care (urgent or elective)
- Ischaemic heart disease and prior myocardial infarction (MI) (using the international definition of MI: Q waves or imaging evidence of regional myocardial akinesis/thinning in the absence of a non-ischemic cause with documentation of prior ischaemic injury) OR other structural heart disease (such as: arrhythmogenic cardiomyopathy (ACM), or dilated cardiomyopathy (DCM), or hypertrophic cardiomyopathy (HCM), or sarcoidosis, or myocarditis).
Exclusion
- Lacks capacity to provide informed consent
- New York Heart Association (NYHA) class IV heart failure
- Life expectancy of less than 12 months
- Implanted with a ventricular assist device
- Presence of mobile intracardiac thrombus
- Reversible cause of VT
- Women who are pregnant or nursing
- Both mechanical aortic and mitral valves
- Enrolment in a concurrent interventional clinical study that in the judgement of the investigator would increase risk to the patient or deem the patient inappropriate to participate in this study.
Key Trial Info
Start Date :
April 11 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 3 2027
Estimated Enrollment :
77 Patients enrolled
Trial Details
Trial ID
NCT06937983
Start Date
April 11 2025
End Date
December 3 2027
Last Update
April 25 2025
Active Locations (1)
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1
University Hospitals Coventry & Warwickshire NHS Trust
Coventry, West Midlands, United Kingdom, CV2 2DX