Status:
RECRUITING
Cardiometabolic evalUation REgistry of Heart Failure
Lead Sponsor:
Ruijin Hospital
Conditions:
Heart Failure
Metabolic Cardiovascular Syndrome
Eligibility:
All Genders
18+ years
Brief Summary
This is a combined retrospective-prospective observational cohort study investigating the role of systemic and local cardiometabolic risk factors in cardiac structural/functional remodeling and clinic...
Detailed Description
This is a combined retrospective-prospective observational cohort study aiming to elucidate the interplay between systemic/localized cardiometabolic risk factors and their impact on myocardial remodel...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Chronic HF (NYHA II\~IV), including:
- HFrEF (HF with reduced ejection fraction): ① HF symptoms±signs ; ② LVEF≤40%.
- HFimpEF (HF with improved ejection fraction): ① HF symptoms±signs; ② previous LVEF ≤ 40% and a follow-up measurement of LVEF \>40%.
- HFmrEF (HF with mildly reduced ejection fraction): ① HF symptoms±signs; ② LVEF 41%\~49%.
- HFpEF (HF with preserved ejection fraction): ① HF symptoms±signs; ② LVEF ≥50%; ③ objective evidence of cardiac structural and/or functional abnormalities consistent with the presence of LV diastolic dysfunction/raised LV filling pressures, including raised natriuretic peptide.
Exclusion
- Estimated survival ≤ 1 year.
- Pregnant or lactation, or have the intention to give birth within one year.
- Poor compliance, unable to follow-up.
- Mental or physical status not allowing written informed consent.
- Unwillingness to give informed consent.
Key Trial Info
Start Date :
January 1 2015
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 31 2030
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT06939985
Start Date
January 1 2015
End Date
May 31 2030
Last Update
April 23 2025
Active Locations (1)
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1
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, China, 200025