Status:

RECRUITING

Preventive Application of Single-use Negative Pressure Wound Therapy (sNPWT) in the Postoperative Course of Radiotreatated Limb Sarcoma Surgery

Lead Sponsor:

Istituto Oncologico Veneto IRCCS

Conditions:

Sarcoma

Sarcoma,Soft Tissue

Eligibility:

All Genders

18-99 years

Phase:

NA

Brief Summary

Patients will be recruited at the time of the pre-admission visit. During the screening visit the patient will undergo a physical examination and his medical history will be collected. Oncological his...

Eligibility Criteria

Inclusion

  • Male or female ≥ 18 years of age
  • diagnosis of primary high-grade (grade III) soft tissue sarcoma of the limbs (confirmed histopathologically)
  • performed neoadjuvant radiotherapy (short or long-term)
  • candidates for wide radical excision surgery
  • negative CT scan staging for distant metastasis
  • Signing of Informed consent

Exclusion

  • diagnosis of benign neoplasm
  • diagnosis of retroperitoneal or trunk sarcomas;
  • candidates to hindquarter or forequarter amputation surgery;
  • incomplete wide excision;
  • vascular resection;
  • other loco-regional treatments (e.g. isolated limb perfusion or electrochemotherapy).

Key Trial Info

Start Date :

September 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2027

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT06941194

Start Date

September 15 2025

End Date

November 1 2027

Last Update

December 2 2025

Active Locations (1)

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1

Istituto Oncologico Veneto

Padua, Italy/Padova, Italy, 35128