Status:
NOT_YET_RECRUITING
Topical Metformin Versus Topical Ketotifen in Melasma Treatment
Lead Sponsor:
Assiut University
Conditions:
Melasma
Eligibility:
All Genders
18-60 years
Phase:
PHASE2
Brief Summary
The study aims to evaluate and compare the efficacy and safety of a new formulation of topical metformin (nanoparticles) versus topical ketotifen (nanoparticles), both alone and combined with micro-ne...
Detailed Description
This research investigates the therapeutic effects of two nanoparticle-based topical treatments-metformin and ketotifen-on melasma. The study employs a split-face design where each patient receives di...
Eligibility Criteria
Inclusion
- Female adults of 18 years and above with bilateral melasma .
- Clinical diagnosis of melasma.
- Mental capacity to give informed consent.
Exclusion
- Pregnant or nursing women.
- Current use of hormonal birth control medication or any hormonal therapy.
- Current or previous treatment by depigmenting agents within 3 months
- History of laser or MN to the face within 3 months of study enrollment.
- Patients with poor wound healing, recurrent herpes simplex and current skin infection (facial warts, molluscum contagiosum) and history of hypertropic scar/keloids.
- Photosensitivity.
- Patients with unrealistic expectations.
Key Trial Info
Start Date :
June 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 30 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06942390
Start Date
June 1 2025
End Date
October 30 2026
Last Update
April 24 2025
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.