Status:

NOT_YET_RECRUITING

Phage Therapy for the Treatment of a Chronic Enterococcus Faecium Periprosthetic Joint Infection

Lead Sponsor:

Orthopaedic Innovation Centre

Collaborating Sponsors:

Cytophage Technologies Inc.

Ottawa Hospital Research Institute

Conditions:

Periprosthetic Joint Infection

Eligibility:

MALE

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

This purpose of this clinical trial is to evaluate the safety, tolerability and efficacy of a bacteriophage therapy in a patient with a methicillin-susceptible Enterococcus faecium (E. faecium) prosth...

Detailed Description

This is a single-patient study, to assess a treatment option for a case of a recurrent methicillin-susceptible E. faecium infection in a prosthetic hip joint. The patient has repeatedly failed standar...

Eligibility Criteria

Inclusion

  • This N-of-1 Phage therapy is designed for one patient who meet the following conditions
  • Willingness to provide signed and dated informed consent form to participate in the clinical study
  • Chronic prosthetic joint infection
  • History of multiple surgical and medication managements with no success

Exclusion

  • below 18 years of age

Key Trial Info

Start Date :

May 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2026

Estimated Enrollment :

1 Patients enrolled

Trial Details

Trial ID

NCT06942624

Start Date

May 1 2025

End Date

June 1 2026

Last Update

April 24 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Concordia Hospital

Winnipeg, Manitoba, Canada, R2K 3S8