Status:

RECRUITING

Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing

Lead Sponsor:

University of Alabama at Birmingham

Conditions:

Stroke

Transient Ischemic Attack (TIA)

Eligibility:

All Genders

18-89 years

Phase:

NA

Brief Summary

The purpose of this research study is to explore whether genetic testing can offer a personalized and timely approach to assist physicians in making more informed medication decisions for stroke or hi...

Detailed Description

This is a pilot clinical trial for feasibility

Eligibility Criteria

Inclusion

  • Patients 18-89 years of age
  • admitted to University of Alabama at Birmingham (UAB) main hospital with symptoms or signs of minor ischemic stroke, or high risk TIA
  • eligible to receive dual antiplatelet load (presented to the hospital within 66 hours of last known well)

Exclusion

  • diagnosis of atrial fibrillation, valvular heart disease, index stroke due to known hypercoagulability (subset of other determined etiology) or large vessel disease (culprit vessel stenosis of ≥50%)
  • prescribed anticoagulation prior to stroke
  • treated with intravenous thrombolysis
  • treated with mechanical thrombectomy
  • missing NIH Stroke Scale score

Key Trial Info

Start Date :

April 9 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2029

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06943586

Start Date

April 9 2025

End Date

April 1 2029

Last Update

April 24 2025

Active Locations (1)

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1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35233