Status:
RECRUITING
Milk Consumption and Blood Microbiome in Healthy Volunteers
Lead Sponsor:
Erasmus Medical Center
Collaborating Sponsors:
NWO (Dutch Organisation for Scientific Research)
Conditions:
Healthy
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The goal of this study is to learn if cfDNA of milk-associated intestinal bacteria (MAIB) is detectable in the bloodstream. The primary question it aims to answer is: \- Does milk consumption simulta...
Detailed Description
eDNA (ecological DNA) is a concept that is gaining popularity for making comprehensive descriptions of all organisms present in an ecosystem. Gut microbiomes can be considered a specific variant of eD...
Eligibility Criteria
Inclusion
- Age 18-65 years
- 5 =\< BMI \< 25 kg/m2
- All genders included
- Not be lactose intolerant
- Willing to consume milk
Exclusion
- Regularly used medications such as antibiotics, steroids, beta blockers, and adrenergic- stimulating agents (self-report)
- Regular use of prebiotic and/or probiotics apart from yogurt and young soft cheese (self-report)
- Antibiotic intake in the previous months (self-report)
- Daily consumption of more than 10 cigarettes (self-report)
- Chronic diseases including type 2 diabetes, hypertension, fatty liver disease, cancer, or autoimmune disease (self-report)
- Internal diseases, including those of the gastrointestinal tract, lung, heart, vasculature, liver, and kidney (self-report)
- Eating disorder or unconventional eating habits (self-report)
- Participation in another study (self-report)
- Women: pregnancy and breastfeeding (self-report)
Key Trial Info
Start Date :
July 10 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 15 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT06944002
Start Date
July 10 2025
End Date
September 15 2025
Last Update
August 7 2025
Active Locations (1)
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1
Erasmus MC - Department of Gastroenterology and Hepatology
Rotterdam, Netherlands, 3015 GD